1990-2019年中国2型糖尿病疾病负担及其变化趋势Disease burden and trends of type 2 diabetes mellitus in China from 1990-2019
王进,李文晓,董春燕,翟燕辉
摘要(Abstract):
目的 分析1990-2019年中国2型糖尿病(T2DM)疾病负担的变化趋势。方法 基于2019年全球疾病负担研究(GBD2019)公开数据库和可视化平台,采用患病率、发病率、死亡率、伤残调整寿命年(DALY)、过早死亡损失寿命年(YLL)、伤残损失寿命年(YLD)及其标化率和平均年度变化百分比(AAPC)等对1990-2019年中国T2DM疾病负担情况进行分析。结果 1990-2019年,中国T2DM患病例数从3 466.75万增加至9 001.76万,发病例数从190.25万上升至373.91万,死亡例数从6.41万上升至16.84万;中国T2DM的总体标化患病率(AAPC=0.68%)、标化发病率(AAPC=0.44%)和标化死亡率(AAPC=0.23%)均呈上升趋势(P均<0.05)。与1990年相比,2019年T2DM的DALY、YLL和YLD分别上升了145.36%、116.69%和163.96%,标化YLL率下降6.7%,标化DALY率和标化YLD率分别上升了9.34%和20.56%。1990-2019年,男性患病率、发病率、死亡率和DALY率的涨幅分别为127.05%、65.10%、162.70%和125.99%,均高于女性涨幅(104.42%、62.51%、87.14%和84.02%)。15~49岁年龄群体在以上指标中涨幅最大,患病率、发病率、死亡率和DALY率的涨幅分别为97.59%,60.37%,24.65%和82.51%。结论 T2DM造成的疾病负担在中国呈上升趋势,应加强T2DM的防控工作,针对重点人群,采取针对性干预措施,以降低T2DM疾病负担。
关键词(KeyWords): 2型糖尿病;患病率;发病率;死亡率;疾病负担
基金项目(Foundation):
作者(Author): 王进,李文晓,董春燕,翟燕辉
DOI: 10.13515/j.cnki.hnjpm.1006-8414.2022.12.004
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